Autobiographical Memories & Brain Stimulation
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Can brain stimulation help to prevent the loss of memories? Entrainment of suppressed oscillations in the aging or pathological brain may be possible and capable to restore lost memory abilities.
Transcranial alternating current stimulation (tACS) is a non-invasive brain stimulation technique that generates an alternating current at a specific frequency, with the potential to synchronize or desynchronize activity between targeted brain regions. As such, tACS represents a powerful tool to causally interfere with the neural correlates of memory and cognition.
- self
- autobiographical memory
- memory loss & preservation
- non-invasive brain stimulation (NIBS)
- Alzheimer’s disease (AD)
- mild cognitive impairment (MCI)
Publications
- Benussi, A., Cantoni, V., Grassi, M., Bréchet, L., Michel, C.M., Datta, A., Thomas, C., Gazing, S., Cotelli, M.S., Bianchi, M., Gadola, Y., Cotelli, M., Pengo, M., Perrone, F., Scolaro, M., Archetti, S., Solse, E., Padovani, A., Pascual-Leone, A., Borroni, B. (2021). Increasing brain gamma activity improves episodic memory and restores cholinergic dysfunction in Alzheimer’s disease. Annals of Neurology.
- Bréchet, L., Michel, C.M., Schacter, D., Pascual-Leone, A. (2021). Improving autobiographical memory in Alzheimer’s disease by transcranial alternating current stimulation. Current Opinions in Behavioral Sciences, 40, 64-71.
- Bréchet, L., Yu, W., Biagi, M.C., Ruffini, G., Gagnon, M., Manor, B., Pascual-Leone, A. (2021). Patient-tailored, home-based non-invasive brain stimulation for memory deficits in dementia due to Alzheimer’s disease. Frontiers in Neurology 12:598135.